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Patch, Plaque, Tumour - Mycosis Fungoides

Mycosis fungoides is a frequent cutaneous lymphoma contributing to an estimated half (50%) of the emerging dermal lymphomas. As an epidermotropic primary cutaneous T lymphoma (CTCL), it may comprise of miniature or medium sized lymphocytes containing cerebriform nuclei and a T helper cell immune phenotype, although variants of a cytotoxic T lymphocyte (CTL) component may commonly arise. “Mycosis Fungoides “as a terminology is restricted to classical manifestation of a disorder characterized by the appearance of patches, plaques and tumours or the diverse cutaneous disorders with an identical clinical evolution. The prevalence of mycosis fungoides is at an estimated 60% of cutaneous tumours, though the incidence may be augmented in the Africans. The lesions may depict a prominent regional variability. Elderly and adult individuals may be frequently incriminated with a male predominance (M:F: 2:1), although children and adolescents may similarly manifest the cutaneous lymphoma


Anubha Bajaj

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