Reach Us 44-7723-59-8358

Hosts and Consequences of Human CoV Infection

Ankita Singh*

Department of Biotechnology, Modern College of Arts, Science and Commerce, Ganeshkhind, Pune, India

*Corresponding Author:
Ankita Singh
Department of Biotechnology, Modern College of Arts, Science and Commerce, Ganeshkhind, Pune, India
E-mail: [email protected]

Received: August 03, 2020; Accepted: August 10, 2020; Published: August 17, 2020

Citation: Singh A (2020) Hosts and Consequences of Human CoV Infection. J Neoplasm Vol.5 No.2:4. doi: 10.36648/2576-3903.5.2.4

 
Visit for more related articles at Journal of Neoplasm

Abstract

Various human Coronaviruses such as Middle East respiratory syndrome coronavirus (MERS-CoV), severe acute respiratory syndrome coronavirus (SARS-CoV), severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) have a different natural host like a bat, mouse and intermediate hosts like a cow, camel, Maylitan Pangolin while human host such as HCoV-NL63, HCoV-OC43, HCoV-229E, HCoV-HKU1 cause mild infection in the human body whereas SARS-CoV-2, MERS-CoV, and SARS-CoV cause mild or severe human disease like respiratory, cardiovascular, digestive disease depending upon the host condition and strain type of viruses. There are various viral receptors such as Angiotensin I-Converting Enzyme 2 (ACE2), ANPEP (also known as CD13), 9-O-acetylated sialic acids (9-0-Ac-Sia); DPP4 (also known as CD26), dipeptidyl peptidase 4 which helps in the invasion. Upon the invasion of SARS-CoV-2, there are structural changes in the host cells found in the human airway epithelial cells (at 96 hours).

image

Select your language of interest to view the total content in your interested language

Viewing options

Flyer image
journal indexing image

Share This Article